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CMP nasal spray for allergic rhinitis
There is a substantial body of experimental data showing that CMP is effective at reducing allergy symptoms against a wide range of common aeroallergens including grass and tree pollens, ragweed, house dust mite as well as dog and cat allergens. CMP Therapeutics is working on developing a simple nasal spray for delivering CMP. The device is a hand-held nasal spray bottle containing a suspension of chitin microparticles (CMP) in sterile saline for the treatment and prevention of allergy symptoms caused by aeroallergens.
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| Unique features of CMP compared to current therapies |
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Enhances the body’s natural defence against allergies |
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and infections |
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Treats the underlying causes of allergic disease |
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Non-toxic, biocompatible, readily degraded by naturally |
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occurring enzymes |
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No side effects |
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Suitable for long-term use |
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Suitable for children |
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Simple and inexpensive to produce |
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CMP is a stable material and easy to formulate |
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Indications for use of CMP nasal spray
The intention is that patients would use CMP nasal spray once or twice a day to control and reduce the symptoms of allergic rhinitis and conjunctivitis during a period of allergen exposure such as would occur in high pollen count months or in the home where there is a high concentration of dust mite or animal dander.
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| The beneficial outcomes of using allermatic |
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Allergy symptom reduction |
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Reduced need for other medicines such as steroid or |
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antihistamines |
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Prevention of the progression of allergic disease into lower airway |
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congestion, cough and asthma |
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Reduce the incidence of upper airway infection |
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Prolonged use of CMP will enhance allergen desensitization |
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through correction of the underlying imbalance in the |
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immune system |
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As a prophylactic for children to protect against the development |
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of allergy and asthma |
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Scientific papers
Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy
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Treatment with chitin microparticles is protective against lung histopathology in a murine asthma model
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Download PDF |
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